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DRUG INTERACTIONSDrug interactions may change how your medications work or increase your risk for serious side effectsThis document does not contain all possible drug interactionsKeep a list of all the products you useincluding prescription/nonprescription drugs and herbal productsand share it with your doctor and pharmacistDo not startstopor change the dosage of any medicines without your doctor’s approval.Some products that may interact with this drug includedrugs to treat erectile dysfunction-ED or pulmonary hypertensionsuch as sildenafiltadalafilriociguat.Check the labels on all your medicinessuch as cough-and-cold productsdiet aidsor NSAIDs such as ibuprofennaproxenbecause they may contain ingredients that could worsen symptoms of heart failureAsk your pharmacist for more details.This medication may interfere with certain laboratory testsincluding cholesterol levelspossibly causing false test resultsMake sure laboratory personnel and all your doctors know you use this drug.

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Isosorbide mononitrate can cause severe headachesespecially when you first start using itThese headaches may gradually become less severe as you continue to use isosorbide mononitrateDo not stop taking the medicationAsk your doctor before using any headache pain medication.

Isosorbide mononitrate is in a group of drugs called nitratesIsosorbide mononitrate dilateswidensblood vesselsmaking it easier for blood to flow through them and easier for the heart to pump.

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